|Restore AutoImmune Thyroiditis with Selenium and Inositol!|
|References: Eur Rev Med Pha Sci, International Jr of Endocrinology, Jr Thyroid Research,
This is quite a remarkable claim. Reversing Hashimoto’s?!! This is like finding the Holy Grail. Hashimoto’s is one of the most common autoimmune diseases in women affecting about 5% of women and 8-15 times as many women as men. There is a robust connection between wheat sensitivity and Hashimoto’s, with celiac disease being documented the most firmly. In the functional medicine world, it goes without saying that Hashimoto’s needs to be managed with the avoidance of gluten. Fasano has been the leading voice in advocating the role of gluten in making leaky gut and subsequent autoimmune disease.
Myo-inositol is new player here. It actually looks like glucose, but it is structured differently. It plays a role in changing membrane signaling. It also plays a role in thyroid activation. Several studies demonstrated that myo-Inositol is the precursor of the synthesis of “phosphoinositides”, which are part of the phosphatidylinositol signal transduction pathway across the plasma membrane, via the second messenger 1,4,5-triphosphate that modulates intracellular calcium release. That means it acts as a second messenger regulating the several like insulin, follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH). And if you understood one word of that paragraph, you get an A.
Bottom line, this unique combination of simple supplements appears to work together to target the missing links in the thyroid dysfunction called Hashimoto’s. That might suggest that anyone might be on the edge of dysfunction, and are then tipped over by an extra stressor, gluten. If we catch you early, you can prevent that tipping and never get in trouble.
1. Hashimoto’s is a rare Japanese thyroid problem. T or F
2. Hashimoto’s damages the thyroid gland leading to all the symptoms of low thyroid. T or F Answer: In a nutshell, yes.
3. You can remarkably improve early Hashimoto’s with selenium and a glucose analog called moo-inositol. Answer: That’s this week’s nugget.
4. The physiology of thyroid function is well understood. T or F Answer: are you kidding, we are just on the surface and continue to be amazed at its complexity and nuance.
5. Getting thyroid right, and selenium right, are critical to healthy brains: Answer: Bingo!!!