Monthly Archives: September 2017

Explaining Biotoxin Illness

References: Surviving Mold,

We are all familiar with bacterial illness. We have experienced sore throats, or skin infections, or sinusitis and have been diagnosed and treated with antibiotics. We have also seen traumatic illness, and have had X-rays and casts or stitches for cuts. We understand metabolic illness with thyroid and sugar and other metabolic parameters. But biotoxin illness? Even the spell checker tries to correct me and call it biotin illness. I mean, BIOTOXIN. This is a whole new field of medicine that will become part of internal medicine or family medicine in the future. For now, it’s just being elucidated and clarified. Here goes my stab at it. This will likely take several weeks to make it a clear story.
In introducing this topic, one has to give credit to Ritchie Shoemaker as the first to understand the new field, the paradigm shift. He was a family physician in Pocomoke, Maryland who persisted in believing his patients who said their were ill in the midst of a pfiesteria bloom on the Pocomoke river. The CDC and Johns Hopkins both came to town for the mystery illness and could not name anything to explain the sick folks symptoms. Dr Shoemaker is now clinically retired but actively teaching new physicians to understand the huge new field through his web site, www.survivingmold.com. One of his patients had terrible diarrhea with the mystery illness. He gave her cholestyramine, an old fashioned cholesterol drug now known to be useless for cholesterol and used mostly to control loose bowels in folks with funny guts. She got better in two days. Not just her stool was better, but her fatigue, her brain fog, her aches and pains – all went away. And then, other patients also got better with cholestyramine.
So, what is biotoxin illness? It is a constellation of symptoms brought on by toxins made by a variety of sources. We are still finding them. Mold in water damaged buildings is likely the most common, with about 30-50% of American buildings being damaged with measurable mold detritus. It’s not the mold spore, but the fragments and protein of many different molds, actinomycetes, volatile organic compounds (VOCs), inflammagens and other yet to be identified components that set off the syndrome. Other causes include aforementioned pfiesteria, a water based dinoflagellate. Lyme disease, spider bites, eating Lion Fish, red tides, the antibiotic CIPRO, multiple wasp stings, beruli ulcer, and probably many more. In weeks to come, we will explain how it may be that some 500,000 Americans are getting Alzheimer’s with mold toxin as a participant.
Most folks are likely fine until they have some trigger that sets them off. Some antecedent event makes them more vulnerable. And they have to be capable of being vulnerable. Turns out roughly 24% of us are genetically “vulnerable”. Our immune systems are unable to see and tag those toxins that will make us ill. We can even measure and find those folks with HLA testing, the same testing you do to see your self identifying proteins that make you you when you need to get a organ transplant. There are patterns Dr Shoemaker has identified that represent the vulnerable and susceptible. The rest of us, 70% are capable of seeing mold toxins and have no trouble getting rid of them. Then there are 2% of us that are catastrophically sensitive.

And what does this illness look like? Simply stated, they check out at ok by typical modern medicine. They express fatigue, brain fog, joints pains, rashes, diarrhea, cough and so many other symptoms that their doctors dismiss them as psychiatric. The house of medicine calls it fibromylagia, or chronic fatigue. And if I told you that 80% of chronic fatigue folks had mold in their urine, would you sit up and pay attention? This needs to be a whole new branch of medicine. Every doctor should know it. It affects 25% of us.

WWW.what will work for me. I’m trying to wrap my head around this way of thinking. It’s a whole new field. If you stick with me, I’m going to keep defining it for you, and learning it for my self. I feel like someone turned on the lights. I’ve tested about 50 people with unexplained fatigue and illness. I’m batting 90% mold as best I can tell. Biotoxin illness. Even my spell checker doesn’t recognize the word.

Pop Quiz

  1. Biotoxin illness is caused by rare bacteria or weird molds? T or F                       Answer: No. It’s is caused by the immune reaction to proteins and broken bits of DNA, or to foreign compounds that alert our innate immune system in a human that doesn’t have the genetic ability to adapt. (Lion fish, red ted, ciguatera, pfiesteria, mold, CIPRO, beruli ulcer, wasp stings….and probably many more)

 

  1. Most of us get sick to these biotoxins when exposed. T or F                              Answer: False. Fully 70% of us have immune systems that see the toxins, tag it, excrete it, done.

 

  1. We can get a simple blood test to measure our risk of biotoxin illness. T or F           Answer: Well, if you consider transplant tissue typing a simple test, sure. But right now it costs some $ 600 bucks and takes a week to get back.

 

  1. Mold illness may play a role in many common illness, like Alzheimer’s.                 Answer: True. But unfair. We haven’t gotten to that yet. Just a hint.

 

  1. So you mean to tell me that that whacko person who walked into our church and said, “I can’t stay here, this place is bad for me,” wasn’t whacko?                     Answer: Hang your head in humility. They were likely one of the 2% who are exquisitely sensitized. Be grateful you don’t live in their skin. And make sure your home is not water damaged.

Juicing is Dangerous for You

Juicing is Dangerous.

References: Advances in NutritionAppetiteEating on the Wild Side,

I get asked all the time about juicing or “smoothies”. Most of the smoothies are described as rich combinations of green vegetables, or yogurt, or fruit. Then, I had someone describe to me how their blood sugar went up almost to 1,000 with a seemingly innocuous concoction. What’s going on that can make that happen?

This column has reviewed the science of changing an apple to apple sauce, then juice before. Barbara Rolls and her team at Penn State observed 58 random volunteer adults for a meal once a week over 5 weeks. Each volunteer was provided a precise “preload” of calories weighing exactly 226 grams with 125 calories in it; aka, one really nice apple. After 15 minutes, they eat whatever they wanted for their meal.

This is what they found. Eating a whole, solid apple resulted in a 15% reduction of calorie intake. That is a 62-calorie reduction for the entire meal. That would be interesting enough by itself. You can lose weight by having an apple 15 minutes before a meal! (62 calories a day is 1800 calories a month or 6 pounds a year.)

But wait, it gets better. Here is the heart of the juicing question. When they changed the apple into applesauce with the same weight, calories, rate of ingestion, timing, resulted in eating 91 calories less overall. Then change the calories into juice. It became 150 calories less.. Applesauce reduced total meal calorie consumption a tiny bit, compared to juice which had virtually no reduction in calories.

The final sword in the experiment was to add fiber added back into the apple juice. Now it becomes a drinkable product, aka juicing. You erase the positive effect of eating a whole apple before a meal. The drinkers did compensate for their calories in the meal, but they did not reduce their total overall calories like eating a whole apple did. It’s interesting that juice, with or without fiber had the same effect. Being liquid just doesn’t register in your brain, no matter the fiber content. Did you get that, juicing erases the message to your brain about content of food.

Our brains and physiology are quite complex. Part of a meal is the actual process of “eating” it. Chewing our food makes a difference in how much food we eat. Stretching it out over time makes a difference. The waiting of 15 minutes before the meal may have been part of the impact. We call that part the cephalic phase during which your body starts to get ready to digest and process food. Managing your cephalic phase sounds like heavy science. Or maybe it’s just plain heavy weight gain.

Here’s my take on it. Eating the whole fruit delivers fiber with the sugar and slows the process of absorbing the sugar dramatically. Mechanically grinding up an apple, or any vegetable, is far more efficient than chewing in terms of mechanically disrupting the cell wall and releasing the sugars inside. When you drink it, you get a burst of glucose delivery to your gut. This results in a burst of insulin release. This results in a burst of LDL production to ship fat to your fat cells instead of energy to your brain and muscles. You thought you ate 800 calories for your meal but your body is saving some of it to fat, because of the insulin burst. Hence, you eat more.

Moral of the story: juicing changing the way you get nutrients: the speed, the mechanics of chewing, the rate of glucose rise all are disrupted. You gain weight.
Now, if you are averse to vegetables and you can’t get them any other way……and aren’t overweight. I’ll relent. If your smoothie is just kale and asparagus and yogurt, I’ll concede. But throw in an apple or a banana, and my skepticism goes up. The heart of the matter is that today’s apple is really much more endowed with sugar than nature’s original apple. Malus Sikimensis, the Himalayan apple is the worlds original, and has a very bitter/sour flavor, sort of like a crab apple. We have changed it into a Golden Delicious, with 1% of it’s original phytonutrients and 10 times its sugar. Hmmm.

www.What will work for me. Eat the whole food. Chew. Sit. Wait. Talk. Enjoy. Visit. The calories you drink are the calories you store. Repeat after me. The calories you drink are the calories you store. Plain and simple.

Pop Quiz

  1. Juicing is really healthy for me?                                                                               Answer: Please reread this column
  2. I hate vegetables. If I juice them, I can get some down. Is that ok?                  Answer: if you keep the high glycemic fruits out of it, you are getting some fiber this way, but be careful if you are trying to lose weight.
  3. The calories I drink are…………                                                                                 Answer:                        The calories I store. (smoothies)
  4. The calories I drink are …………….                                                                            Answer: The calories I store (beer).
  5. The hormonal effect of food is more important for weight control than the quality of the food. T or F                                                                                                                  Answer: True. That’s the secret behind this message. Smoothies make glucose be delivered too fast, turning on insulin. Insulin is your storage hormone. The exact same food, delivered slowly and with fiber built in makes for a different metabolic product.

 

 

Upcoming Seminar: The End of Alzheimer’s

Save the Date  Oct 14th, Saturday Morning

“The End of Alzheimer’s”

NO-ONE Should Ever Get This Awful Disease

Yes, that is possible, for you and for your loved ones.

And it is reversible if we catch you early enough.

Dale Bredesen has proven it, and we will explain his methods.  You will learn the details of how you can protect yourself, what life style changes you can make, how you can measure your success, what lab tests you can order and what supplements you should be adding.  We will detail the various pathways by which our brains get injured, resulting in Alzheimer’s.  You will leave knowing at least 10 specific things you can start doing today to keep your brain healthy and vibrant into your 90s.

Dr John Whitcomb and MD Custom Pharmacy are collaborating to bring you this important information.

Saturday Morning:  Oct 14Th 4th.   4 hours and we will feed you lunch.  2 lectures and an hour of questions and answers.  Then, a demonstration luncheon on how you should be eating.

To Register:  Call MD Custom Pharmacy   262-373-1050

Place:  Beautiful Redeemer Church on Townline Road in Sussex (Just south of Townline and Lisbon Road Stop Light.  We will start at 8 am with coffee and greeting.

Price:  $ 35 for the first early registrants.  $ 45 in the last week.  We can only seat a limited number so please call now and save your spot.

Restore Hashimoto’s Thyroid Function with Selenium and Myo-Inositol

Restore AutoImmune Thyroiditis with Selenium and Inositol!

 

References: Eur Rev Med Pha SciInternational Jr of EndocrinologyJr Thyroid Research,

This is quite a remarkable claim. Reversing Hashimoto’s?!! This is like finding the Holy Grail. Hashimoto’s is one of the most common autoimmune diseases in women affecting about 5% of women and 8-15 times as many women as men. There is a robust connection between wheat sensitivity and Hashimoto’s, with celiac disease being documented the most firmly. In the functional medicine world, it goes without saying that Hashimoto’s needs to be managed with the avoidance of gluten. Fasano has been the leading voice in advocating the role of gluten in making leaky gut and subsequent autoimmune disease.
This study took 168 patients with TPO or anti-thyroglobulin antibodies and a TSH between 3-6. That’s quite modest Hashimoto’s. The higher the TPO, the more damaged the thyroid gland is, and the more prolonged course has been already endured. The free T4 and free T3 levels were still “normal”. They were randomized to receive either 83 mg of selenium or 83 ng if selenium and 600 mg of myo-inositol for 6 months. The combination group had a better response and recovered their thyroid function better and felt better to boot. This isn’t the first study to prove this effect, but it is the largest.
Certainly we know the role of selenium, at least to some degree. The enzyme that catalyzes the production of free T3 has to lop off the fourth iodine of T4. It is called de-iodinase. It is based on the selenium atom. If you want to do a deep dive into de-iodinase, the ZRT blog has an excellent summary. Leave it sufficient to understand that there are three forms of de-iodinase which all help conserve iodine, balance thyroid function by maintaining the level of free T3 is a healthful range and responding to stress and starvation. There is less selenium in mid-westAmerican soil, lots in Rocky Mountain soils. Hence, selenium deficiency is common.

Myo-inositol is new player here. It actually looks like glucose, but it is structured differently. It plays a role in changing membrane signaling. It also plays a role in thyroid activation. Several studies demonstrated that myo-Inositol is the precursor of the synthesis of “phosphoinositides”, which are part of the phosphatidylinositol signal transduction pathway across the plasma membrane, via the second messenger 1,4,5-triphosphate that modulates intracellular calcium release. That means it acts as a second messenger regulating the several like insulin, follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH). And if you understood one word of that paragraph, you get an A.

Bottom line, this unique combination of simple supplements appears to work together to target the missing links in the thyroid dysfunction called Hashimoto’s. That might suggest that anyone might be on the edge of dysfunction, and are then tipped over by an extra stressor, gluten. If we catch you early, you can prevent that tipping and never get in trouble.
WWW.What will work for me. Well, selenium is that critical element we all appear to be a bit short of. If you are reading this in Wyoming, you are likely getting enough because your soils have it. If you are in Wisconsin, you probably need to take a supplement. I’m intrigued that Bredesen considers it a critical part of his Alzheimer’s pathway. That makes me in. Selenium is important.

 

Pop Quiz

1. Hashimoto’s is a rare Japanese thyroid problem. T or F
Answer: False. It is common the world over, with up to 5% of women affected

2. Hashimoto’s damages the thyroid gland leading to all the symptoms of low thyroid. T or F Answer: In a nutshell, yes.

3. You can remarkably improve early Hashimoto’s with selenium and a glucose analog called moo-inositol. Answer: That’s this week’s nugget.

4. The physiology of thyroid function is well understood. T or F Answer: are you kidding, we are just on the surface and continue to be amazed at its complexity and nuance.

5. Getting thyroid right, and selenium right, are critical to healthy brains: Answer: Bingo!!!

 

 

Generosity is Good for YOU

References: PsychNETHealth PsychologyCurr Dir Psychol Sci-FiScience,

Alright! We just had a huge hurricane in Texas, and another on the way in the Atlantic. The TV and radio are all calling out for help with money, time, boats, you name it. They need help. They need your generosity. And here is what is cool, you do too!

Giving, at first, feels hard. You worked hard for your dollars. You earned your good salary. But why does every religious tradition in history consider helping people one of their central tenants? Jesus, as one example, talks more about giving away your wealth than any other topic. Jewish tradition is what Jesus was referencing. They are just as generous. It’s one of the Five Pillars of Islam. Buddhism has “10 Good Deeds“. Hindu’s get to heaven giving alms.

Modern researchers are finally putting some “scientific data” around that. Why is “giving” so important for us to learn to do? What is it about generosity that makes it so compelling, despite the barriers of self interest?

Here is the science of it. In 2013, a study of retired representing a statistical sample of America was conducted. They had to be over 50 and multiple variables were recorded over 4 years of observation. Those who volunteered more than 200 hours in the 12 months prior to the study being started showed they developed less high blood pressure (40% less). That’s about the same effect as taking a pill. They also had high scores on “well being”. This is pretty remarkable. But that’s not all.

Another study looked at elderly folks given $ 40 and told they had to dispose of it in one day. Half were to spend it on themselves. The other half had to give it away. Guess what happened! Those who had to give it away dropped their blood pressure as much as folks taking a pill to lower pressure. This reinforces other research that shows that “Happiness Runs in a Circular Motion.” There is plenty of other research showing that the closer you are involved, the stronger the emotional tie. Up front and personal matters.

I get it. Every religion says it’s good because the geniuses of history expressed their insight into human nature as rules for us to follow for daily living. It’s good for you. Plain and simple. Thank goodness there are folks around who need our help. That applies to the poorest of the poor.

WWW.What will work for me. One of my strongest childhood memories from Bisrampur church in India was the “Muthi Dhan” offering where the local farmers would bring in a “fistful of rice” to share with those more needy. These were folks living on $ 3-5 a day for their whole family. They would qualify in just about anyone’s lexicon as being poor, and needing help. But their own happiness depends on giving too. I’m intending to go to my current congregation and give a meaningfully big check towards hurricane relief. I would ask you do do that same, for your sake.

Pop Quiz

  1. Something about the way we got wired as humans gets into a good spot when we share what is important and precious to us with others? T or F
    Answer: Call it your faith, your duty, your community, but yes, isn’t that true.
  2. We can measure medical consequences of being generous. What is it?               Answer: Blood pressure lowering as much as with a pill
  3. Is this why brain health experts say to keep a healthy brain, you need to be connected? Answer: You decide. Of course!
  4. I’m too poor to give. T or F                                                                             Answer: Research shows the “poor”tend to be more generous, proportionately.
  5. Most money is given by the poor? T or F                                               Answer: actually false. 70-80% of total dollars comes from “wealthy”, but they are giving a lower percentage of their income. So, don’t trash the rich. Praise them for their generosity. It’s really important for them to be connected too.  I suspect that the mind set of “accumulating wealth” becomes a habit, then an addiction, making giving all the harder, and all the more important.  It appears it’s a habit not broken easily, hence the religious admonitions.